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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
25.15
Human Site:
S1630
Identified Species:
42.56
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1630
Q
P
L
F
R
P
R
S
E
F
E
E
M
T
I
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1419
P
R
A
Y
E
P
R
S
E
F
E
Q
M
T
I
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
S350
A
T
A
A
F
R
G
S
S
D
L
P
F
G
A
Dog
Lupus familis
XP_543382
1925
209302
S1632
Q
P
L
F
R
P
R
S
E
F
E
E
M
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1692
Q
P
L
F
R
P
R
S
E
F
E
E
M
T
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
R421
P
A
F
G
S
A
S
R
E
T
D
Y
R
R
P
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1715
Q
P
Q
F
R
P
R
S
E
F
E
E
M
T
I
Frog
Xenopus laevis
Q66J90
1938
216239
S1645
R
A
M
F
K
P
R
S
E
F
E
E
M
T
I
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1550
R
P
S
F
M
P
R
S
D
F
E
E
M
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
H1366
I
K
M
S
Y
L
D
H
L
H
K
E
P
Y
A
Honey Bee
Apis mellifera
XP_395451
1406
159180
D1132
S
Y
E
A
L
L
A
D
D
S
Q
G
Y
W
L
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
E1233
A
L
N
E
M
Q
S
E
V
K
S
A
D
E
L
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
D1635
Q
K
P
T
P
S
P
D
K
V
E
P
A
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
R1039
D
A
E
L
W
L
W
R
R
N
R
I
R
Q
L
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
60
6.6
100
N.A.
100
N.A.
N.A.
6.6
93.3
73.3
73.3
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
73.3
6.6
100
N.A.
100
N.A.
N.A.
13.3
93.3
93.3
86.6
N.A.
20
20
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
22
15
15
0
8
8
0
0
0
0
8
8
0
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
15
15
8
8
0
8
0
0
% D
% Glu:
0
0
15
8
8
0
0
8
50
0
58
50
0
8
0
% E
% Phe:
0
0
8
43
8
0
0
0
0
50
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
50
% I
% Lys:
0
15
0
0
8
0
0
0
8
8
8
0
0
0
0
% K
% Leu:
0
8
22
8
8
22
0
0
8
0
8
0
0
0
22
% L
% Met:
0
0
15
0
15
0
0
0
0
0
0
0
50
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
15
36
8
0
8
50
8
0
0
0
0
15
8
8
8
% P
% Gln:
36
0
8
0
0
8
0
0
0
0
8
8
0
8
0
% Q
% Arg:
15
8
0
0
29
8
50
15
8
0
8
0
15
8
0
% R
% Ser:
8
0
8
8
8
8
15
58
8
8
8
0
0
0
0
% S
% Thr:
0
8
0
8
0
0
0
0
0
8
0
0
0
50
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
8
8
0
0
0
0
0
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _